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 D08 Enzymes and Coenzymes D045762 +
  D08.811 Enzymes D004798 +
   D08.811.913 Transferases D014166 +
    D08.811.913.555 One-Carbon Group Transferases D019875 +
     D08.811.913.555.500 Methyltransferases D008780 +
      D08.811.913.555.500.250 Catechol O-Methyltransferase D002394