All

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 C05 Musculoskeletal Diseases D009140 +
  C05.660 Musculoskeletal Abnormalities D009139 +
   C05.660.207 Craniofacial Abnormalities D019465 +
    C05.660.207.410 Holoprosencephaly D016142 
 C10 Nervous System Diseases D009422 +
  C10.500 Nervous System Malformations D009421 +
   C10.500.410 Holoprosencephaly D016142 
 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.131 Abnormalities D000013 +
   C16.131.077 Abnormalities, Multiple D000015 +
    C16.131.077.410 Holoprosencephaly D016142 
 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.131 Abnormalities D000013 +
   C16.131.260 Chromosome Disorders D025063 +
    C16.131.260.380 Holoprosencephaly D016142 
 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.131 Abnormalities D000013 +
   C16.131.621 Musculoskeletal Abnormalities D009139 +
    C16.131.621.207 Craniofacial Abnormalities D019465 +
     C16.131.621.207.410 Holoprosencephaly D016142 
 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.131 Abnormalities D000013 +
   C16.131.666 Nervous System Malformations D009421 +
    C16.131.666.410 Holoprosencephaly D016142 
 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.320 Genetic Diseases, Inborn D030342 +
   C16.320.180 Chromosome Disorders D025063 +
    C16.320.180.380 Holoprosencephaly D016142