All

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 C18 Nutritional and Metabolic Diseases D009750 +
  C18.452 Metabolic Diseases D008659 +
   C18.452.660 Mitochondrial Diseases D028361 +
     C18.452.660.300 Friedreich Ataxia D005621 
     C18.452.660.520 Leigh Disease D007888 
     C18.452.660.705 Pyruvate Carboxylase Deficiency Disease D015324 
     C18.452.660.710 Pyruvate Dehydrogenase Complex Deficiency Disease D015325 
     C18.452.660.560 Mitochondrial Myopathies D017240 +
     C18.452.660.665 Optic Atrophy, Autosomal Dominant D029241 
     C18.452.660.515 Optic Atrophy, Hereditary, Leber D029242 
     C18.452.660.195 Cytochrome-c Oxidase Deficiency D030401