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 C21 Disorders of Environmental Origin D007280 +
  C21.739 Substance-Related Disorders D019966 +
   C21.739.675 Opioid-Related Disorders D009293 +
    C21.739.675.400 Heroin Dependence D006556 
 F03 Mental Disorders D001523 +
  F03.900 Substance-Related Disorders D019966 +
   F03.900.675 Opioid-Related Disorders D009293 +
    F03.900.675.400 Heroin Dependence D006556