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 C06 Digestive System Diseases D004066 +
  C06.405 Gastrointestinal Diseases D005767 +
   C06.405.469 Intestinal Diseases D007410 +
    C06.405.469.860 Rectal Diseases D012002 +
     C06.405.469.860.101 Anus Diseases D001004 +
      C06.405.469.860.101.752 Pruritus Ani D011538 
 C17 Skin and Connective Tissue Diseases D017437 +
  C17.800 Skin Diseases D012871 +
   C17.800.685 Pruritus D011537 +
    C17.800.685.544 Pruritus Ani D011538