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 C10 Nervous System Diseases D009422 +
  C10.292 Cranial Nerve Diseases D003389 +
   C10.292.700 Optic Nerve Diseases D009901 +
    C10.292.700.225 Optic Atrophy D009896 +
     C10.292.700.225.500 Optic Atrophies, Hereditary D015418 +
      C10.292.700.225.500.980 Wolfram Syndrome D014929 
 C10 Nervous System Diseases D009422 +
  C10.574 Neurodegenerative Diseases D019636 +
   C10.574.500 Heredodegenerative Disorders, Nervous System D020271 +
    C10.574.500.662 Optic Atrophies, Hereditary D015418 +
     C10.574.500.662.980 Wolfram Syndrome D014929 
 C11 Eye Diseases D005128 +
  C11.270 Eye Diseases, Hereditary D015785 +
   C11.270.564 Optic Atrophies, Hereditary D015418 +
    C11.270.564.980 Wolfram Syndrome D014929 
 C11 Eye Diseases D005128 +
  C11.640 Optic Nerve Diseases D009901 +
   C11.640.451 Optic Atrophy D009896 +
    C11.640.451.451 Optic Atrophies, Hereditary D015418 +
     C11.640.451.451.980 Wolfram Syndrome D014929 
 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.131 Abnormalities D000013 +
   C16.131.077 Abnormalities, Multiple D000015 +
    C16.131.077.951 Wolfram Syndrome D014929 
 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.320 Genetic Diseases, Inborn D030342 +
   C16.320.290 Eye Diseases, Hereditary D015785 +
    C16.320.290.564 Optic Atrophies, Hereditary D015418 +
     C16.320.290.564.980 Wolfram Syndrome D014929 
 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.320 Genetic Diseases, Inborn D030342 +
   C16.320.400 Heredodegenerative Disorders, Nervous System D020271 +
    C16.320.400.630 Optic Atrophies, Hereditary D015418 +
     C16.320.400.630.980 Wolfram Syndrome D014929 
 C18 Nutritional and Metabolic Diseases D009750 +
  C18.452 Metabolic Diseases D008659 +
   C18.452.394 Glucose Metabolism Disorders D044882 +
    C18.452.394.750 Diabetes Mellitus D003920 +
     C18.452.394.750.099 Diabetes Mellitus, Type I D003922 +
      C18.452.394.750.099.960 Wolfram Syndrome D014929 
 C19 Endocrine Diseases D004700 +
  C19.246 Diabetes Mellitus D003920 +
   C19.246.267 Diabetes Mellitus, Type I D003922 +
    C19.246.267.960 Wolfram Syndrome D014929 
 C19 Endocrine Diseases D004700 +
  C19.700 Pituitary Diseases D010900 +
   C19.700.482 Hypopituitarism D007018 +
    C19.700.482.215 Diabetes Insipidus D003919 +
     C19.700.482.215.960 Wolfram Syndrome D014929