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 G05 Genetic Processes D039361 +
  G05.315 Gene Expression Regulation D005786 +
   G05.315.200 Down-Regulation D015536 
 G06 Biochemical Phenomena, Metabolism, and Nutrition D001670 +
  G06.184 Biochemical Phenomena D001669 +
   G06.184.320 Down-Regulation D015536 
 G07 Physiological Processes D010829 +
  G07.621 Homeostasis D006706 +
   G07.621.487 Feedback, Biochemical D025461 +
    G07.621.487.500 Down-Regulation D015536 
 G12 Chemical and Pharmacologic Phenomena D002620 +
  G12.307 Down-Regulation D015536