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 C05 Musculoskeletal Diseases D009140 +
  C05.660 Musculoskeletal Abnormalities D009139 +
   C05.660.585 Limb Deformities, Congenital D017880 +
     C05.660.585.350 Ectromelia D004480 
     C05.660.585.800 Syndactyly D013576 +
     C05.660.585.984 Thanatophoric Dysplasia D013796 
     C05.660.585.620 Proteus Syndrome D016715 
     C05.660.585.600 Polydactyly D017689 +
     C05.660.585.512 Lower Extremity Deformities, Congenital D038061 
     C05.660.585.988 Upper Extremity Deformities, Congenital D038062 

 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.131 Abnormalities D000013 +
   C16.131.621 Musculoskeletal Abnormalities D009139 +
    C16.131.621.585 Limb Deformities, Congenital D017880 +
      C16.131.621.585.350 Ectromelia D004480 
      C16.131.621.585.380 Foot Deformities, Congenital D005532 
      C16.131.621.585.425 Hand Deformities, Congenital D006228 
      C16.131.621.585.800 Syndactyly D013576 +
      C16.131.621.585.984 Thanatophoric Dysplasia D013796 
      C16.131.621.585.620 Proteus Syndrome D016715 
      C16.131.621.585.600 Polydactyly D017689 +
      C16.131.621.585.512 Lower Extremity Deformities, Congenital D038061 
      C16.131.621.585.988 Upper Extremity Deformities, Congenital D038062