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 C05 Musculoskeletal Diseases D009140 +
  C05.660 Musculoskeletal Abnormalities D009139 +
   C05.660.207 Craniofacial Abnormalities D019465 +
     C05.660.207.207 Cleidocranial Dysplasia D002973 
     C05.660.207.231 Craniofacial Dysostosis D003394 +
     C05.660.207.240 Craniosynostoses D003398 +
     C05.660.207.620 Microcephaly D008831 
     C05.660.207.690 Noonan Syndrome D009634 
     C05.660.207.700 Orofaciodigital Syndromes D009958 
     C05.660.207.720 Platybasia D010985 
     C05.660.207.850 Rubinstein-Taybi Syndrome D012415 
     C05.660.207.410 Holoprosencephaly D016142 
     C05.660.207.540 Maxillofacial Abnormalities D019767 +
     C05.660.207.525 LEOPARD Syndrome D044542 

 C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities D009358 +
  C16.131 Abnormalities D000013 +
   C16.131.621 Musculoskeletal Abnormalities D009139 +
    C16.131.621.207 Craniofacial Abnormalities D019465 +
      C16.131.621.207.207 Cleidocranial Dysplasia D002973 
      C16.131.621.207.231 Craniofacial Dysostosis D003394 +
      C16.131.621.207.240 Craniosynostoses D003398 +
      C16.131.621.207.620 Microcephaly D008831 
      C16.131.621.207.690 Noonan Syndrome D009634 
      C16.131.621.207.700 Orofaciodigital Syndromes D009958 
      C16.131.621.207.720 Platybasia D010985 
      C16.131.621.207.850 Rubinstein-Taybi Syndrome D012415 
      C16.131.621.207.410 Holoprosencephaly D016142 
      C16.131.621.207.540 Maxillofacial Abnormalities D019767 +
      C16.131.621.207.525 LEOPARD Syndrome D044542